Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 15/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894622 | 0.88 | PRCP (0.68) | PRCP | |
| SCHEMBL12175464 | 0.86 | PRCP (0.76) | PRCPOPRD1 | |
| SCHEMBL12175472 | 0.85 | PRCP (1.00) | PRCP | |
| SCHEMBL12175470 | 0.83 | PRCP (0.69) | PRCPOPRM1OPRD1OPRK1 | |
| SCHEMBL14650874 | 0.83 | PRCP (0.72) | PRCP | |
| SCHEMBL12175718 | 0.82 | PRCP (0.81) | PRCP | |
| SCHEMBL12175515 | 0.82 | PRCP (0.69) | PRCPOPRD1 | |
| SCHEMBL12175549 | 0.82 | PRCP (0.86) | PRCP | |
| SCHEMBL12175514 | 0.82 | PRCP (0.72) | PRCPOPRD1 | |
| SCHEMBL14650811 | 0.82 | PRCP (0.72) | PRCPOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785634-B2 | Spiropiperidine prolylcarboxypeptidase inhibitors | MERCK SHARP & DOHME CORP (US) | 2014-07-22 | — | — | US | disclosed |