Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899650 | 0.95 | EGLN1 (0.80) | EGLN1 | |
| SCHEMBL622247 | 0.89 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL15899673 | 0.88 | EGLN1 (0.79) | EGLN1 | |
| SCHEMBL10230211 | 0.84 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL15899536 | 0.83 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL15899723 | 0.83 | EGLN1 (0.80) | EGLN1 | |
| SCHEMBL15899705 | 0.82 | EGLN1 (0.79) | EGLN1 | |
| SCHEMBL15899671 | 0.81 | EGLN1 (0.81) | EGLN1 | |
| SCHEMBL15899578 | 0.80 | EGLN1 (0.81) | EGLN1 | |
| SCHEMBL15899570 | 0.80 | EGLN1 (0.79) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603502-B1 | 4-AMINOQUINAZOLIN-2-YL-1-PYRRAZOLE-4-CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-07-30 | — | — | EP | claimed |