Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 20/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899668 | 0.91 | HDAC8 (0.73) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899691 | 0.89 | HDAC8 (0.73) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899830 | 0.88 | HDAC8 (0.74) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899724 | 0.88 | HDAC8 (0.75) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL442448 | 0.86 | HDAC8 (1.00) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899735 | 0.85 | HDAC8 (0.74) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899649 | 0.85 | HDAC8 (0.74) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899659 | 0.84 | HDAC8 (0.74) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899664 | 0.84 | HDAC8 (0.74) | HDAC8HDAC6HDAC1HDAC7HDAC9 | |
| SCHEMBL15899722 | 0.84 | HDAC8 (0.79) | HDAC8HDAC6HDAC1HDAC7HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613775-B1 | N-HYDROXY-BENZAMIDES FOR THE TREATMENT OF CANCER | HOFFMANN LA ROCHE (CH) | 2014-07-30 | — | — | EP | claimed |