SCHEMBL1589974

SCHEMBL1589974

CC(C)(c1ccccc1)S(=O)(=O)O.[Zn]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP2C19 P33261 2/20 0.42
HIF1A Q16665 1/20 0.42
PTPN1 P18031 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619 0.98 MAPT (0.45) MAPTKMT2ACYP2C19HIF1APTPN1
Ammonia Solution, Strong SCHEMBL340602 0.95 MAPT (0.43) MAPTKMT2ACYP2C19HIF1APTPN1
SCHEMBL1589914 0.95 MAPT (0.43) MAPTKMT2ACYP2C19HIF1APTPN1
SCHEMBL15880618 0.95 MAPT (0.43) MAPTKMT2ACYP2C19HIF1APTPN1
SCHEMBL22345146 0.95 MAPT (0.43) MAPTKMT2ACYP2C19HIF1APTPN1
Ammonia Solution, Strong SCHEMBL8406673 0.93 MAPT (0.42) MAPTKMT2ACYP2C19HIF1APTPN1
SCHEMBL778852 0.78 MAPK1 (0.44) MAPTKMT2ACYP2C19HIF1AALDH1A1
SCHEMBL9120864 0.77 PTPN1 (0.50) MAPTKMT2ACYP2C19HIF1APTPN1
SCHEMBL7596921 0.77 TSHR (0.48) MAPTKMT2AALDH1A1TSHRCA1
SCHEMBL13241630 0.77 CYP2C19 (0.44) MAPTKMT2ACYP2C19HIF1APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491079-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2016-07-20 EP disclosed
EP-2491079-A1 THERMOPLASTIC POLYMER COMPOSITION Milliken & Company (US) 2012-08-29 EP disclosed
US-8198351-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2012-06-12 US disclosed
WO-2011050042-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2011-04-28 WO disclosed
US-20110092625-A1 THERMOPLASTIC POLYMER COMPOSITION MILLKEN & COMPANY 2011-04-21 US disclosed