Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674429 | 1.00 | AKT1 (0.56) | AKT1AKT2 | |
| SCHEMBL1674427 | 1.00 | AKT1 (0.56) | AKT1AKT2 | |
| SCHEMBL15900007 | 0.92 | AKT1 (0.53) | AKT1AKT2 | |
| SCHEMBL1674534 | 0.92 | AKT1 (0.53) | AKT1AKT2 | |
| SCHEMBL1674434 | 0.89 | AKT1 (0.58) | AKT1AKT2 | |
| SCHEMBL1674433 | 0.89 | AKT1 (0.58) | AKT1AKT2 | |
| SCHEMBL15900011 | 0.87 | AKT1 (0.55) | AKT1AKT2 | |
| SCHEMBL1674704 | 0.87 | AKT1 (0.55) | AKT1AKT2 | |
| SCHEMBL15900008 | 0.84 | AKT1 (0.53) | AKT1AKT2 | |
| SCHEMBL1674481 | 0.84 | AKT1 (0.53) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303269-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2014-07-30 | — | — | EP | claimed |
| EP-2303269-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2014-07-30 | — | — | EP | disclosed |