⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28185442 | 0.89 | — | — | |
| Thiocyanic Acid SCHEMBL28436585 | 0.64 | — | — | |
| SCHEMBL27920554 | 0.64 | — | — | |
| SCHEMBL3648895 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL28731821 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL28935112 | 0.62 | — | — | |
| SCHEMBL589950 | 0.61 | — | — | |
| Water SCHEMBL7537804 | 0.61 | — | — | |
| SCHEMBL5494828 | 0.59 | — | — | |
| SCHEMBL19260288 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655616-A | Chiral 6-hydroxypyridine oxazoline compound, preparation method and application | 闽都创新实验室 | 2023-08-29 | — | — | CN | claimed |
| CN-113735851-B | Synthesis method of visible light promoted 3-phenylimidazo [1, 5-alpha ] pyridine-1-nitrile | 怀化学院 | 2022-12-13 | — | — | CN | claimed |
| CN-114409590-A | Compound with dihydropyridinitrile structure and preparation method and application thereof | 河南新中飞照明电子有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-113735851-A | Synthesis method of visible light promoted 3-phenylimidazo [1, 5-alpha ] pyridine-1-nitrile | 怀化学院 | 2021-12-03 | — | — | CN | claimed |
| CN-110003889-A | A kind of small molecule emitter material and the preparation method and application thereof based on three loop coil acridine donor monomers | 华南理工大学 | 2019-07-12 | — | — | CN | claimed |
| EP-1491201-B1 | Methods of reducing toxicity of 5-fluorouracil with acylated pyrimidine nucleosides | WELLSTAT THERAPEUTICS CORP (US) | 2006-03-22 | — | — | EP | claimed |
| EP-0831849-A4 | METHODS OF REDUCING TOXICITY OF CHEMOTHERAPEUTIC AND ANTIVIRAL AGENTS WITH ACYLATED PYRIMIDINE NUCLEOSIDES | WELLSTAT THERAPEUTICS CORP (US) | 2003-03-26 | — | — | EP | claimed |
| US-6344447-B2 | ADMINISTERING MIXTURE OF NUCLEOSIDES; ANTICANCER AGENT | PRO-NEURON, INC. | 2002-02-05 | — | — | US | claimed |
| US-20010025032-A1 | TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES | VON BORSTEL REID W (US) | 2001-09-27 | — | — | US | claimed |
| US-5968914-A | Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides | PRO-NEURON, INC. (US) | 1999-10-19 | — | — | US | claimed |
| EP-0831849-A1 | METHODS OF REDUCING TOXICITY OF CHEMOTHERAPEUTIC AND ANTIVIRAL AGENTS WITH ACYLATED PYRIMIDINE NUCLEOSIDES | PRO-NEURON, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040165-A1 | METHODS OF REDUCING TOXICITY OF CHEMOTHERAPEUTIC AND ANTIVIRAL AGENTS WITH ACYLATED PYRIMIDINE NUCLEOSIDES | PRO-NEURON, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| CN-116655616-B | Chiral 6-hydroxypyridine oxazoline compound, preparation method and application | 闽都创新实验室 | 2025-11-04 | — | — | CN | disclosed |
| WO-2023169569-A1 | TRICYCLIC HETEROCYCLE COMPOUNDS AS IAP ANTAGONISTS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2023-09-14 | — | — | WO | disclosed |
| CN-116655616-A | Chiral 6-hydroxypyridine oxazoline compound, preparation method and application | 闽都创新实验室 | 2023-08-29 | — | — | CN | disclosed |
| CN-116655616-A | Chiral 6-hydroxypyridine oxazoline compound, preparation method and application | 闽都创新实验室 | 2023-08-29 | — | — | CN | disclosed |
| US-4931525-A | Optical active (meth)acrylamides and polymers thereof for racemate resolution | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| US-4914159-A | Optically active (meth)acrylamides, a process for their preparation, and their use for racemate resolution | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
| EP-0218089-B1 | OPTICALLY ACTIVE (METH)-ACRYL AMIDE, POLYMERS THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF RACEMATES | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |
| EP-0218089-A1 | Optically active (meth)-acryl amide, polymers thereof, process for their preparation and their use in the separation of racemates | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |