Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.51 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 5/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1591130 | 0.92 | CSNK1D (0.45) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1590513 | 0.88 | CSNK1D (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1590813 | 0.88 | CSNK1D (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1590512 | 0.88 | CSNK1D (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL3590041 | 0.88 | CSNK1D (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1590726 | 0.86 | CSNK1D (0.38) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1591506 | 0.81 | CSNK1D (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1591535 | 0.81 | EGFR (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1591536 | 0.81 | EGFR (0.41) | CSNK1DCSNK1ECDK13CDK12ABL1 | |
| SCHEMBL1591791 | 0.80 | CSNK1D (0.48) | CSNK1DCSNK1ECDK13CDK12ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092491-A1 | Compounds and Compositions as Inhibitors of Receptor Tyrosine Kinase Activity | NOVARTIS AG (CH) | 2011-04-21 | — | — | US | disclosed |
| US-20050124637-A1 | Compounds and compositions as inhibitors of receptor tyrosine kinase activity | IRM LLC (BM) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124637-A1 | Compounds and compositions as inhibitors of receptor tyrosine kinase activity | BMX, LCK, FYN | CSNK1D 812/4885CSNK1E 500/4885CDK13 1128/4885 |
| US-20110092491-A1 | Compounds and Compositions as Inhibitors of Receptor Tyrosine Kinase Activity | BMX, LCK, FYN | CSNK1D 812/4885CSNK1E 500/4885CDK13 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.