⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389194 | 1.00 | — | — | |
| SCHEMBL16389193 | 1.00 | — | — | |
| SCHEMBL25485097 | 1.00 | — | — | |
| SCHEMBL20329195 | 0.95 | — | — | |
| SCHEMBL21393146 | 0.95 | — | — | |
| SCHEMBL24211073 | 0.95 | — | — | |
| SCHEMBL20649715 | 0.95 | — | — | |
| SCHEMBL13882148 | 0.95 | — | — | |
| SCHEMBL20438310 | 0.90 | — | — | |
| SCHEMBL15492641 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8790919-B2 | Compositions and methods for optimizing cleavage of RNA by RNase H | ISIS PHARMACEUTICALS, INC. (US) | 2014-07-29 | — | — | US | disclosed |