Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906090 | 1.00 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL16158908 | 1.00 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL13578443 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL13578440 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL13578444 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL10440260 | 0.88 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL4330690 | 0.88 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3795508 | 0.88 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL15906123 | 0.84 | HCRTR2 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL15906115 | 0.84 | HCRTR2 (0.47) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140301999-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2014-10-09 | — | — | US | disclosed |
| US-8791267-B2 | Biaryl PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders | DECODE GENETICS EHF (IS) | 2014-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140301999-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | PDE4A, PDE4B, PDE3B | HCRTR1 2509/4885HCRTR2 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.