Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.72 |
| ▸ | STING1 | Q86WV6 | 14/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106673 | 1.00 | KMT2A (0.76) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL1133093 | 1.00 | KMT2A (0.76) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL10239446 | 1.00 | KMT2A (0.76) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL23829872 | 0.87 | RXFP1 (0.82) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL23829800 | 0.87 | RXFP1 (0.82) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL23829726 | 0.87 | RXFP1 (0.82) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL23829728 | 0.87 | RXFP1 (0.82) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL10098850 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL4159569 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 | |
| SCHEMBL29515507 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1RAPGEF3RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765844-B1 | PURINE NUCLEOTIDE DERIVATIVES | SOLVELL AS (NO) | 2014-07-30 | — | — | EP | disclosed |