SCHEMBL15906342

SCHEMBL15906342

Cc1ccc(C(=C/C=C/c2ccc(/C=C/c3ccc(Cl)cc3)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.55
MAOA P21397 3/20 0.55
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
PTGS2 P35354 3/20 0.45
ALOX5 P09917 2/20 0.45
PTGS1 P23219 2/20 0.45
NPC1 O15118 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.42
NFE2L2 Q16236 2/20 0.40
AHR P35869 1/20 0.40
RAB9A P51151 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15900045 1.00 MAOB (0.55) MAOBMAOACES2CES1PTGS2
SCHEMBL15907940 0.83 GPR183 (0.45) MAOBMAOAPTGS2ALOX5PTGS1
SCHEMBL15908721 0.83 MAOB (0.43) MAOBMAOAPTGS2NPC1ALDH1A1
SCHEMBL15900234 0.83 MAOB (0.53) MAOBMAOACES2CES1PTGS2
SCHEMBL15906334 0.83 MAOB (0.53) MAOBMAOACES2CES1PTGS2
SCHEMBL15906344 0.82 MAPT (0.41) MAOBMAOAPTGS2ALOX5PTGS1
SCHEMBL15906332 0.82 MAPT (0.41) MAOBMAOAPTGS2ALOX5PTGS1
SCHEMBL15900022 0.82 MAPT (0.41) MAOBMAOAPTGS2ALOX5PTGS1
SCHEMBL2423808 0.80 MAPT (0.42) MAOBMAOAPTGS2ALOX5PTGS1
SCHEMBL15275156 0.80 MAPT (0.42) MAOBMAOAPTGS2ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759530-B1 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same TAKASAGO PERFUMERY CO LTD (JP) 2015-09-23 EP disclosed
US-9128393-B2 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-09-08 US disclosed
US-9128393-B2 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-09-08 US disclosed
US-20140213822-A1 TRIPHENYLAMINE DERIVATIVE, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-31 US disclosed
US-20140213822-A1 TRIPHENYLAMINE DERIVATIVE, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-31 US disclosed
EP-2759530-A1 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same Takasago International Corporation (JP) 2014-07-30 EP disclosed