SCHEMBL15907718

SCHEMBL15907718

CC1(C)c2ccccc2-c2ccc(N(c3ccc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)cc3)c3cc4c5c(ccc6cc(-c7ccc(C#N)cc7)cc(c65)C4(C)C)c3)cc21

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.39
PGR P06401 1/20 0.31
MYC P01106 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15907721 0.88 PDK2 (0.30) PDK2
SCHEMBL15909622 0.87 PDK2 (0.40) PDK2PGR
SCHEMBL15907510 0.87 PDK2 (0.32) PDK2
SCHEMBL15909767 0.87 PDK2 (0.41) PDK2PGRMYC
SCHEMBL15909828 0.85 PDK2 (0.46) PDK2PGRMYC
SCHEMBL15316828 0.85 PDK2 (0.35) PDK2
SCHEMBL15907720 0.84 ABCG2 (0.30)
SCHEMBL19770664 0.84 PDK2 (0.32) PDK2
SCHEMBL17118483 0.83 PDK2 (0.30) PDK2
SCHEMBL15907442 0.83 PDK2 (0.32) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9773987-B2 Silicon-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-09-26 US disclosed
US-20140209869-A1 SILICON-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2014-07-31 US disclosed