Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051406 | 0.85 | PARP1 (0.69) | PARP1ARTSHR | |
| SCHEMBL15908002 | 0.83 | PARP1 (0.69) | PARP1 | |
| SCHEMBL3387433 | 0.83 | PARP1 (0.70) | PARP1ARTSHR | |
| SCHEMBL4434823 | 0.82 | PARP1 (1.00) | PARP1 | |
| SCHEMBL905602 | 0.80 | PARP1 (0.76) | PARP1ARTSHR | |
| SCHEMBL15908003 | 0.78 | PARP1 (0.57) | PARP1 | |
| SCHEMBL24000680 | 0.78 | PARP1 (0.63) | PARP1ARTSHR | |
| SCHEMBL4439381 | 0.78 | PARP1 (1.00) | PARP1ARTSHR | |
| SCHEMBL4433410 | 0.77 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30741471 | 0.77 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9283222-B2 | Inhibitors of poly(ADP-ribose)polymerase | ABBVIE INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140212509-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBVIE INC. (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212509-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | PARP1, PARP2, PARP3 | PARP1 1/4885AR 3000/4885TSHR 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.