SCHEMBL15908615

SCHEMBL15908615

c1ccc(-c2cc(-c3ccc(-c4ccc5c(c4)-n4c6ccccc6c6cccc(c64)C54c5ccccc5-c5ccccc54)cc3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.35
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP19A1 P11511 1/20 0.31
DHODH Q02127 1/20 0.30
FLT3 P36888 1/20 0.30
BMX P51813 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15908653 0.99 DUSP3 (0.34) PDK2DUSP3FLT3BMXKDM4E
SCHEMBL15908619 0.93 MEN1 (0.36) PDK2DUSP3MEN1KMT2AFLT3
SCHEMBL15908616 0.93 PDK2 (0.37) PDK2DUSP3MEN1KMT2ACYP19A1
SCHEMBL15908624 0.93 MEN1 (0.36) PDK2DUSP3MEN1KMT2AFLT3
SCHEMBL15908614 0.93 PDK2 (0.36) PDK2DUSP3MEN1KMT2ACYP19A1
SCHEMBL15908651 0.92 PDK2 (0.35) PDK2DUSP3FLT3BMXKDM4E
SCHEMBL15908649 0.91 DUSP3 (0.35) PDK2DUSP3FLT3BMXKDM4E
SCHEMBL15908623 0.91 PDK2 (0.34) PDK2DUSP3FLT3BMXKDM4E
SCHEMBL15908654 0.90 MAPT (0.36) DUSP3MEN1KMT2AFLT3BMX
SCHEMBL15908617 0.89 PDK2 (0.35) PDK2MEN1KMT2ACYP19A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed