Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908887 | 0.87 | MAPT (0.56) | HDAC8FAAH | |
| SCHEMBL4183681 | 0.86 | CYP4A11 (0.52) | HPGDEPHX2FAAHPDE3BPDE3A | |
| SCHEMBL1743875 | 0.86 | CYP4A11 (0.52) | HPGDEPHX2FAAHPDE3BPDE3A | |
| SCHEMBL8997287 | 0.84 | CYP4A11 (0.54) | HPGDEPHX2FAAHPDE3BPDE3A | |
| SCHEMBL10982252 | 0.84 | CYP4F2 (0.50) | ADRB2ADRB1CYP4F2CYP4A11 | |
| SCHEMBL7971302 | 0.84 | HDAC8 (0.44) | HDAC8FAAH | |
| SCHEMBL7968451 | 0.84 | HDAC8 (0.44) | HDAC8FAAH | |
| SCHEMBL7970617 | 0.84 | HDAC8 (0.44) | HDAC8FAAH | |
| SCHEMBL7955579 | 0.84 | HDAC8 (0.44) | HDAC8FAAH | |
| SCHEMBL25262780 | 0.83 | CYP4F2 (0.60) | ADRB2ADRB1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796205-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-08-05 | — | — | US | disclosed |