Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 18/20 | 1.00 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.71 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19381620 | 0.84 | S1PR5 (0.72) | S1PR5S1PR1S1PR3 | |
| SCHEMBL322452 | 0.83 | S1PR5 (1.00) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL18550086 | 0.80 | S1PR5 (0.67) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL320912 | 0.79 | S1PR5 (0.65) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL15164300 | 0.79 | S1PR5 (0.79) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL320988 | 0.78 | S1PR5 (1.00) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL15909517 | 0.76 | S1PR5 (1.00) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL3669682 | 0.74 | S1PR5 (0.72) | S1PR5S1PR1S1PR3FFAR1 | |
| SCHEMBL18550345 | 0.74 | S1PR5 (0.62) | S1PR5S1PR1S1PR3 | |
| SCHEMBL18549832 | 0.73 | S1PR5 (0.61) | S1PR5S1PR1S1PR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48301-E1 | Fused heterocyclic derivatives as S1P modulators | ABBVIE B.V. (NL) | 2020-11-10 | — | — | US | claimed |
| US-8796262-B2 | Fused heterocyclic derivatives as S1P modulators | ABBVIE B.V. (NL) | 2014-08-05 | — | — | US | claimed |
| US-RE48301-E1 | Fused heterocyclic derivatives as S1P modulators | ABBVIE B.V. (NL) | 2020-11-10 | — | — | US | disclosed |
| US-8796262-B2 | Fused heterocyclic derivatives as S1P modulators | ABBVIE B.V. (NL) | 2014-08-05 | — | — | US | disclosed |
| US-8796262-B2 | Fused heterocyclic derivatives as S1P modulators | ABBVIE B.V. (NL) | 2014-08-05 | — | — | US | disclosed |