SCHEMBL15910001

SCHEMBL15910001

COC(=O)c1ccc(-c2nc(-c3ccc(-c4nc(-c5ccc(C(=O)OC)cc5)nc(-c5ccccc5O)n4)cc3)nc(-c3ccccc3O)n2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
NPSR1 Q6W5P4 2/20 0.60
POLB P06746 1/20 0.60
KDM4A O75164 1/20 0.59
EGFR P00533 1/20 0.55
TSHR P16473 2/20 0.53
ALOX15 P16050 2/20 0.53
ADORA3 P0DMS8 1/20 0.53
ADORA2A P29274 1/20 0.53
ADORA2B P29275 1/20 0.53
ADORA1 P30542 1/20 0.53
ALDH1A1 P00352 6/20 0.51
HPGD P15428 5/20 0.51
GAA P10253 3/20 0.51
IDO1 P14902 1/20 0.49
PTPN1 P18031 2/20 0.49
PTPRC P08575 1/20 0.49
PTPRF P10586 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608388 1.00 MAPT (0.60) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL12228440 0.97 EGFR (0.59) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL13887102 0.96 EGFR (0.62) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL15908092 0.94 MAPT (0.55) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608434 0.94 MAPT (0.58) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL15908071 0.93 MAPT (0.57) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608454 0.93 MAPT (0.57) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608460 0.93 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL12997148 0.93 MAPT (0.54) MAPTMEN1KMT2ANPSR1POLB
SCHEMBL9608462 0.92 MAPT (0.56) MAPTMEN1KMT2ANPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975314-B2 Triazine derivative and ultraviolet absorber FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-20140213703-A1 NEW TRIAZINE DERIVATIVE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2014-07-31 US disclosed