Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.77 |
| ▸ | PDGFRB | P09619 | 10/20 | 0.77 |
| ▸ | KDR | P35968 | 10/20 | 0.77 |
| ▸ | FLT1 | P17948 | 7/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052212 | 0.87 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL1082404 | 0.82 | FGFR1 (0.77) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3383639 | 0.80 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL6186855 | 0.78 | FGFR1 (0.69) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL12879833 | 0.78 | FGFR1 (0.70) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL14795893 | 0.76 | FGFR1 (0.57) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL30737932 | 0.75 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL30457708 | 0.75 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL1177582 | 0.75 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL1050162 | 0.75 | FGFR1 (1.00) | FGFR1PDGFRBKDRFLT1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762475-A1 | Pharmaceutically acceptable salts of quinolinone compounds and their medical use | Novartis Vaccines and Diagnostics, Inc. (US) | 2014-08-06 | — | — | EP | disclosed |