SCHEMBL15911367

SCHEMBL15911367

CC(C)N1CCC(NC(=O)Oc2cc3cc(Cl)ccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.67
F2 P00734 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15911509 0.94 F10 (0.64) F10F2
SCHEMBL15911631 0.93 F10 (0.78) F10F2
SCHEMBL15911364 0.92 F10 (0.61) F10F2
SCHEMBL8358964 0.88 F10 (0.86) F10F2
SCHEMBL3231945 0.86 F10 (0.55) F10F2
SCHEMBL15911391 0.86 F10 (0.59) F10F2
SCHEMBL1675374 0.82 F10 (0.81) F10F2
SCHEMBL3372965 0.82 F10 (0.66) F10F2
SCHEMBL3246474 0.81 F10 (0.78) F10F2
SCHEMBL15911439 0.81 F10 (0.77) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451185-B1 INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2014-08-06 EP claimed