Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911285 | 0.90 | F10 (0.51) | F10F2DRD4SIGMAR1CNR1 | |
| SCHEMBL15911529 | 0.88 | F10 (0.55) | F10F2 | |
| SCHEMBL1675000 | 0.86 | F10 (0.70) | F10F2CCR2 | |
| SCHEMBL15911269 | 0.85 | F10 (0.58) | F10F2DRD4MCHR1SIGMAR1 | |
| SCHEMBL15911538 | 0.84 | F10 (0.75) | F10F2 | |
| SCHEMBL15911645 | 0.83 | F10 (0.52) | F10F2DRD4 | |
| SCHEMBL15911394 | 0.82 | F10 (0.80) | F10F2 | |
| SCHEMBL15911496 | 0.78 | F10 (0.51) | F10F2 | |
| SCHEMBL15911421 | 0.78 | F10 (0.66) | F10F2 | |
| SCHEMBL15911648 | 0.77 | F10 (0.47) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | claimed |