Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911543 | 0.92 | F10 (0.64) | F10MAPTMCHR1F2CYP3A4 | |
| SCHEMBL15911354 | 0.90 | F10 (0.75) | F10F2CYP3A4CYP2D6HTR4 | |
| SCHEMBL1675138 | 0.87 | F10 (1.00) | F10MCHR1F2 | |
| SCHEMBL15911677 | 0.86 | F10 (0.64) | F10F2CYP3A4CYP2D6HTR4 | |
| SCHEMBL15911308 | 0.85 | F10 (0.74) | F10F2 | |
| SCHEMBL15911398 | 0.85 | F10 (0.60) | F10MAPTMCHR1DRD4 | |
| SCHEMBL15911708 | 0.84 | F10 (0.78) | F10MCHR1DRD4F2 | |
| SCHEMBL15911534 | 0.84 | F10 (0.59) | F10MAPTMCHR1DRD4 | |
| SCHEMBL15911445 | 0.83 | F10 (0.69) | F10MCHR1DRD4F2 | |
| SCHEMBL15911525 | 0.80 | F10 (0.65) | F10DRD4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | claimed |