Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 15/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911891 | 1.00 | S1PR1 (0.62) | S1PR1S1PR3TDP1L3MBTL1MEN1 | |
| SCHEMBL17302133 | 0.83 | S1PR1 (0.63) | S1PR1S1PR3MEN1KMT2AALDH1A1 | |
| SCHEMBL17295555 | 0.80 | S1PR3 (0.73) | S1PR1S1PR3MEN1KMT2AALDH1A1 | |
| SCHEMBL17295556 | 0.80 | S1PR3 (0.73) | S1PR1S1PR3MEN1KMT2AALDH1A1 | |
| SCHEMBL17295332 | 0.79 | S1PR1 (0.60) | S1PR1S1PR3MEN1KMT2AALDH1A1 | |
| SCHEMBL17295333 | 0.79 | S1PR1 (0.60) | S1PR1S1PR3MEN1KMT2AALDH1A1 | |
| SCHEMBL17309290 | 0.79 | MEN1 (0.79) | S1PR1S1PR3TDP1L3MBTL1MEN1 | |
| SCHEMBL12013235 | 0.79 | MEN1 (0.79) | S1PR1S1PR3TDP1L3MBTL1MEN1 | |
| SCHEMBL11331663 | 0.79 | MEN1 (0.79) | S1PR1S1PR3TDP1L3MBTL1MEN1 | |
| SCHEMBL11331666 | 0.79 | MEN1 (0.79) | S1PR1S1PR3TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2489662-B1 | Intermediates of a new process for the preparation of 5-benzylidene-2-alkylimino-3-phenylthiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2014-08-06 | — | — | EP | disclosed |