SCHEMBL15915210

SCHEMBL15915210

COc1ccc(-c2nc3ccc(-c4ccc(C(N)=O)cc4)cn3c2CCN2CCCN(C)CC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 15/20 0.49
▸ SLC2A2 P11168 1/20 0.44
▸ CHKA P35790 1/20 0.44
▸ MTNR1A P48039 2/20 0.42
▸ MTNR1B P49286 2/20 0.42
▸ TSPO P30536 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12818917 0.92 SLC2A1 (0.59) SLC2A1CHKA
SCHEMBL15914075 0.87 SLC2A1 (0.49) SLC2A1SLC2A2
SCHEMBL15914748 0.84 SLC2A1 (0.49) SLC2A1SLC2A2CHKA
SCHEMBL15914576 0.84 SLC2A1 (0.49) SLC2A1SLC2A2CHKA
SCHEMBL12819117 0.82 SLC2A1 (0.67) SLC2A1CHKA
SCHEMBL12819202 0.81 SLC2A1 (0.74) SLC2A1
SCHEMBL15914991 0.81 SLC2A1 (0.44) SLC2A1SLC2A2CHKAMTNR1AMTNR1B
SCHEMBL15914472 0.79 SLC2A1 (0.69) SLC2A1SLC2A2
SCHEMBL15915208 0.79 SLC2A1 (0.40) SLC2A1CHKATSPO
SCHEMBL12818473 0.79 SLC2A1 (0.58) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM TECHNOLOGY TRANSFER GMBH (DE) 2014-08-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY HIF1A, HIF1AN, EGLN3 SLC2A1 1235/4885SLC2A2 1610/4885CHKA 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback