SCHEMBL159167

SCHEMBL159167

C1CCC([SiH2]CC2CC2)OC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17239053 1.00
SCHEMBL17239041 0.98
SCHEMBL157438 0.98
SCHEMBL447072 0.96
SCHEMBL443566 0.94 HPGD (0.31)
SCHEMBL12814193 0.94 HPGD (0.31)
SCHEMBL6355739 0.94 HPGD (0.31)
SCHEMBL29168773 0.89
SCHEMBL2724024 0.81 TSHR (0.31)
SCHEMBL15845356 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758032-B1 COMPOSITIONS AND METHODS FOR TREATING CONDITIONS OF COMPROMISED SKIN BARRIER FUNCTION SHISEIDO AMERICAS CORP (US) 2021-10-27 EP claimed
EP-2780425-A1 RAPID CURE SILICONE LUBRICIOUS COATINGS Ethicon, Inc. (US) 2014-09-24 EP claimed
WO-2013074732-A1 RAPID CURE SILICONE LUBRICIOUS COATINGS ETHICON, INC. (US) 2013-05-23 WO claimed
EP-1801163-B1 Siloxane Encapsulants ROHM & HAAS (US) 2009-08-05 EP claimed
US-7485682-B2 Thermoplastic elastomer composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-02-03 US claimed
US-7150919-B2 Overmolded grip THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-12-19 US claimed
US-7015284-B2 Thermoplastic elastomer composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-03-21 US claimed
US-20060052535-A1 Thermoplastic elastomer composition COLORMATRIX HOLDINGS, INC. 2006-03-09 US claimed
US-20050148727-A1 Thermoplastic elastomer composition COLORMATRIX HOLDINGS, INC. 2005-07-07 US claimed
US-20040151933-A1 Overmolded grip GOODYEAR TIRE & RUBBER COMPANY, THE 2004-08-05 US claimed
WO-2003078527-A1 ADDITION CURABLE SILICONE GUM HAVING IMPROVED THERMAL CONDUCTIVITY DOW CORNING CORPORATION (US) 2003-09-25 WO claimed
US-6015869-A SORBENT COPOLYMERS(OR OLIGOMERS) CONTAINING ALKYL-SUBSTITUTED FLUORINATED BISPHENOL MONOMERS ALTERNATING WITH SILOXANE MONOMERS, FOR SENSITIVE THIN FILMS ON SENSORS OR CLADDING ON OPTICAL FIBERS BATTELLE MEMORIAL INSTITUTE (US) 2000-01-18 US claimed
EP-0586845-B1 Method of bonding using polycarborane siloxane polymers HUGHES AIRCRAFT CO (US) 1997-09-03 EP claimed
EP-0398573-A2 Devices featuring silicone elastomers AT&T Corp. (US) 1990-11-22 EP claimed
JP-11199588-A None JP disclosed
JP-11189598-A None JP disclosed
US-20240191044-A1 ULTRA-THIN ELASTOMER SHEET AND METHOD FOR PRODUCING SAME ASAHI FR R&D CO., LTD. (JP) 2024-06-13 US disclosed
EP-0711779-A1 Sunscreens, cosmetic sunscreen compositions and uses thereof L'OREAL (FR) 1996-05-15 EP disclosed
EP-0708108-A1 Solar filtres, cosmetic sunscreen compositions containing them, and their application L'OREAL (FR) 1996-04-24 EP disclosed
US-5441560-A Organopolysiloxane and mixed additive package consists of zinc oxide, antimony oxide and a brominated compound; useful for sealing and protecting electrical contacts RAYCHEM CORPORATION (US) 1995-08-15 US disclosed