Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176138 | 0.83 | ACACB (0.56) | ACACBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL1106944 | 0.79 | KMT2A (0.51) | ACACBTSHRGAAKMT2AGFER | |
| SCHEMBL18176112 | 0.73 | ACACB (0.50) | ACACBTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL14441191 | 0.72 | KMT2A (0.60) | GAAKMT2AGFERMEN1ALDH1A1 | |
| SCHEMBL13494840 | 0.71 | NPC1 (0.74) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL29135907 | 0.70 | SMN1; SMN2 (0.73) | TSHRGAAKMT2AGFERMEN1 | |
| SCHEMBL6421498 | 0.70 | ESR1 (0.48) | ACACBTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL2691862 | 0.70 | ESR1 (0.48) | ACACBTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6966307 | 0.70 | ACACB (0.54) | ACACB | |
| SCHEMBL15022611 | 0.70 | ACACB (0.54) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014114578-A1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-31 | — | — | WO | disclosed |