Naphthalene

Naphthalene

SCHEMBL15918862

C=CCc1ccccc1.c1ccc2ccccc2c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
ALDH1A1 P00352 3/20 0.45
ALOX12 P18054 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
CNR2 P34972 2/20 0.42
CYP2A6 P11509 1/20 0.40
XDH P47989 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ARG2 P78540 1/20 0.40
CALM1 P0DP23 1/20 0.39
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL6153986 0.95 MAOB (0.48) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL21274 0.92
Allylbenzene SCHEMBL2478260 0.92 MAOB (0.60) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL10325179 0.92 MAOB (0.60) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL6417054 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL5697714 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL2051491 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL12004553 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL16752547 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53
Allylbenzene SCHEMBL7203197 0.90 MAOB (0.57) MAOBALDH1A1ALOX12SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140217016-A1 BIOMEDIATION METHOD BIOSTRYKE REMEDIATION PRODUCTS, LLC 2014-08-07 US claimed
CN-104379710-B Working fluid composition for refrigerating machine 吉坤日矿日石能源株式会社 2016-08-31 CN disclosed
CN-104379710-A Working fluid composition for refrigerating machine JX NIPPON OIL & ENERGY CORP 2015-02-25 CN disclosed