Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760526 | 0.81 | TSHR (0.44) | SMN1; SMN2TSHRNPSR1EPHX1USP2 | |
| SCHEMBL21660010 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRNPSR1EPHX1USP2 | |
| SCHEMBL12535887 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRNPSR1EPHX1USP2 | |
| SCHEMBL11922817 | 0.77 | FUCA1 (0.50) | SMN1; SMN2TSHRNPSR1EPHX1POLB | |
| SCHEMBL25120945 | 0.77 | EPHX1 (0.43) | SMN1; SMN2TSHRNPSR1EPHX1USP2 | |
| SCHEMBL23374529 | 0.76 | FUCA1 (0.36) | SMN1; SMN2TSHRNPSR1EPHX1ALDH1A1 | |
| SCHEMBL23374497 | 0.76 | FUCA1 (0.36) | SMN1; SMN2TSHRNPSR1EPHX1ALDH1A1 | |
| SCHEMBL21619467 | 0.75 | S1PR1 (0.51) | EPHX1 | |
| Alcohol SCHEMBL14109310 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRNPSR1EPHX1USP2 | |
| SCHEMBL3698326 | 0.75 | S1PR1 (0.41) | SMN1; SMN2TSHRNPSR1EPHX1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | SMN1; SMN2 3450/4885TSHR 449/4885CARM1 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.