Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.41 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920127 | 0.85 | NPY2R (0.49) | NPY2RMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15920094 | 0.85 | NPY2R (0.53) | NPY2RTRPV1ALDH1A1HTTRECQL | |
| SCHEMBL15920315 | 0.75 | NPY2R (0.55) | NPY2RCYP2C9MEN1KMT2ASERPINE1 | |
| SCHEMBL15920122 | 0.73 | HPGD (0.58) | NPY2RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13873647 | 0.72 | NPY2R (0.75) | NPY2RMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13883824 | 0.70 | NPY2R (0.61) | NPY2RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8735896 | 0.70 | NPY2R (0.73) | NPY2RMAPTMEN1KMT2A | |
| SCHEMBL13873608 | 0.70 | NPY2R (0.73) | NPY2RMAPTMEN1KMT2A | |
| SCHEMBL8737920 | 0.70 | NPY2R (0.60) | NPY2RTRPV1MAPTMEN1KMT2A | |
| SCHEMBL13890091 | 0.69 | NPY2R (0.59) | NPY2RMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |