Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920322 | 0.90 | NPY2R (0.49) | NPY2RSMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL15920088 | 0.84 | NPY2R (0.53) | NPY2RSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15919734 | 0.83 | NPY2R (0.54) | NPY2RMAPTALDH1A1MEN1CYP2C19 | |
| SCHEMBL15920126 | 0.82 | NPY2R (0.54) | NPY2RSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15920119 | 0.82 | NPY2R (0.52) | NPY2RMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15920124 | 0.81 | NPY2R (0.53) | NPY2R | |
| SCHEMBL15920211 | 0.80 | NPY2R (0.63) | NPY2R | |
| SCHEMBL15920081 | 0.80 | NPY2R (0.48) | NPY2RSMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL15920226 | 0.80 | NPY2R (0.53) | NPY2RMEN1CYP2C19KMT2A | |
| SCHEMBL15920228 | 0.79 | NPY2R (0.54) | NPY2RSMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |