Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 9/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 9/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920601 | 0.91 | MAPK10 (0.65) | MAPK9MAPK10MAPK8LTA4HHRH3 | |
| SCHEMBL15920603 | 0.91 | MAPK9 (0.80) | MAPK9MAPK10MAPK8TP53LTA4H | |
| SCHEMBL15920592 | 0.90 | MAPK9 (0.61) | MAPK9MAPK10MAPK8LTA4HTBK1 | |
| SCHEMBL3748955 | 0.90 | MAPK10 (0.81) | MAPK9MAPK10MAPK8TP53RAB9A | |
| SCHEMBL15920444 | 0.89 | MAPK9 (0.61) | MAPK9MAPK10MAPK8LTA4HTBK1 | |
| SCHEMBL3740598 | 0.83 | MAPK10 (0.85) | MAPK9MAPK10MAPK8TP53RAB9A | |
| SCHEMBL3753376 | 0.83 | MAPK10 (0.70) | MAPK9MAPK10MAPK8TP53RAB9A | |
| SCHEMBL4200034 | 0.81 | MAPK10 (0.84) | MAPK9MAPK10MAPK8TP53RAB9A | |
| SCHEMBL15920645 | 0.81 | MAPK10 (0.61) | MAPK9MAPK10MAPK8NPC1 | |
| SCHEMBL3746727 | 0.80 | MAPK10 (0.79) | MAPK9MAPK10MAPK8RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014114186-A1 | JNK INHIBITORS | 山东亨利医药科技有限责任公司 (CN) | 2014-07-31 | — | — | WO | disclosed |