SCHEMBL15924902

SCHEMBL15924902

C=CCC=C(C#N)C(=O)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CYP2C9 P11712 1/20 0.33
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27410309 0.81 ADORA2A (0.40) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL29087667 0.81 CYP2C9 (0.39) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL541315 0.78 CYP2C9 (0.56) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL29087652 0.78 CYP2C9 (0.37) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL22319321 0.78 CYP2C9 (0.36) MEN1KMT2ACYP2C9POLBTDP1
SCHEMBL9753255 0.77 MEN1 (0.33) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL9753252 0.77 MEN1 (0.33) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL17813318 0.76 KDM4E (0.35) KDM4EMEN1KMT2ANPC1USP2
SCHEMBL1155521 0.75
SCHEMBL4074959 0.73 TP53 (0.46) KDM4EMEN1KMT2ANPC1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US claimed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US claimed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP claimed
US-8877309-B1 Self-repairing inflatable articles DRY CAROLYN M (US) 2014-11-04 US claimed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO claimed
US-10011149-B2 Self-repairing inflatable articles DRY CAROLYN M (US) 2018-07-03 US disclosed
US-9694629-B1 Self-repairing inflatable articles incorporating an integrated self-repair system Dry, Carolyn (US) 2017-07-04 US disclosed
US-9683816-B2 Self-repairing armor Dry, Carolyn (US) 2017-06-20 US disclosed
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US disclosed
US-20160195367-A1 SELF-REPAIRING ARMOR DRY CAROLYN (US) 2016-07-07 US disclosed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US disclosed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP disclosed
US-20150056391-A1 SELF-REPAIRING INFLATABLE ARTICLES DRY CAROLYN M (US) 2015-02-26 US disclosed
US-8877309-B1 Self-repairing inflatable articles DRY CAROLYN M (US) 2014-11-04 US disclosed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO disclosed