Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 13/20 | 0.58 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16831398 | 0.88 | GBA1 (0.68) | FEN1ALOX5APGBA1 | |
| SCHEMBL16831309 | 0.88 | GBA1 (0.68) | FEN1ALOX5APGBA1 | |
| SCHEMBL31494043 | 0.88 | GBA1 (0.68) | FEN1ALOX5APGBA1 | |
| SCHEMBL16831311 | 0.88 | GBA1 (0.68) | FEN1ALOX5APGBA1 | |
| SCHEMBL16831474 | 0.77 | GBA1 (0.47) | FEN1ALOX5APGBA1GRIA4 | |
| SCHEMBL16831477 | 0.77 | GBA1 (0.47) | FEN1ALOX5APGBA1GRIA4 | |
| SCHEMBL15924905 | 0.77 | GRIA4 (0.52) | FEN1ALOX5APGBA1GRIA4 | |
| SCHEMBL15915636 | 0.76 | RECQL (0.54) | FEN1ALOX5APGBA1 | |
| SCHEMBL16831811 | 0.76 | FEN1 (0.55) | FEN1ALOX5APGBA1 | |
| SCHEMBL15915633 | 0.76 | RECQL (0.54) | FEN1ALOX5APGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | claimed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | claimed |