Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932671 | 0.83 | BRAF (1.00) | BRAF | |
| SCHEMBL15925278 | 0.76 | BRAF (0.69) | BRAF | |
| SCHEMBL3058233 | 0.75 | BRAF (1.00) | BRAF | |
| SCHEMBL3754492 | 0.73 | BRAF (1.00) | BRAF | |
| SCHEMBL2931091 | 0.72 | BRAF (1.00) | BRAF | |
| SCHEMBL9909711 | 0.72 | BRAF (0.76) | BRAF | |
| SCHEMBL2976693 | 0.72 | BRAF (1.00) | BRAF | |
| SCHEMBL4476197 | 0.72 | BRAF (1.00) | BRAF | |
| SCHEMBL9909785 | 0.70 | BRAF (0.66) | BRAF | |
| SCHEMBL15925246 | 0.70 | BRAF (0.54) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229391-B1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | CANCER REC TECH LTD (GB) | 2014-08-06 | — | — | EP | disclosed |