Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925290 | 1.00 | IL6ST (0.50) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL24418522 | 0.93 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL27133027 | 0.89 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL27133026 | 0.89 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL15925285 | 0.89 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL23461757 | 0.89 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL15925288 | 0.89 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL5500159 | 0.89 | IL6ST (0.54) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL5065686 | 0.87 | PPARA (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL21153769 | 0.87 | PPARA (0.49) | IL6STPPARANAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796474-B1 | Macrolide compounds and methods and intermediates useful for their preparation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-08-05 | — | — | US | disclosed |