Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925694 | 1.00 | IDO1 (0.32) | IDO1CYP19A1CCNCCDK8FFAR2 | |
| SCHEMBL15925712 | 1.00 | IDO1 (0.32) | IDO1CYP19A1CCNCCDK8FFAR2 | |
| SCHEMBL15925725 | 0.91 | ROCK1 (0.37) | CYP19A1FFAR2CHEK2 | |
| SCHEMBL15925723 | 0.90 | MAPK1 (0.35) | FFAR2F2RL1 | |
| SCHEMBL15925701 | 0.90 | MAPK1 (0.35) | IDO1CYP19A1F2RL1PTGDR2 | |
| SCHEMBL15925711 | 0.90 | MAPK1 (0.35) | IDO1CYP19A1F2RL1PTGDR2 | |
| SCHEMBL15925705 | 0.90 | MAPK1 (0.35) | FFAR2F2RL1 | |
| SCHEMBL15925703 | 0.90 | MAPK1 (0.35) | IDO1CYP19A1F2RL1PTGDR2 | |
| SCHEMBL15925728 | 0.90 | MAPK1 (0.35) | FFAR2F2RL1 | |
| SCHEMBL15925715 | 0.89 | CYP19A1 (0.35) | CYP19A1FFAR2CHEK2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796271-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |