SCHEMBL15925845

SCHEMBL15925845

Cc1ccc(Sc2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)c(F)c2)cc1C

nearest known ligand 0.85

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 20/20 0.85
S1PR3 Q99500 12/20 0.80
S1PR4 O95977 2/20 0.51
S1PR5 Q9H228 2/20 0.51
S1PR2 O95136 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10168141 0.92 S1PR1 (1.00) S1PR1S1PR3
SCHEMBL10168143 0.89 S1PR1 (1.00) S1PR1S1PR3
SCHEMBL10168135 0.89 S1PR1 (1.00) S1PR1S1PR3
SCHEMBL10168117 0.87 S1PR1 (0.63) S1PR1S1PR3S1PR4S1PR5
Hydrochloric Acid SCHEMBL589366 0.86 S1PR1 (0.62) S1PR1S1PR3S1PR4S1PR5
SCHEMBL10168154 0.81 S1PR1 (1.00) S1PR1S1PR3
SCHEMBL10168145 0.80 S1PR1 (0.80) S1PR1S1PR3
SCHEMBL10168161 0.80 S1PR1 (0.75) S1PR1S1PR3
SCHEMBL590242 0.80 S1PR1 (0.78) S1PR1S1PR3
SCHEMBL588792 0.78 S1PR1 (0.76) S1PR1S1PR3S1PR4S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017257-B1 2-AMINOBUTANOL COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES MITSUBISHI TANABE PHARMA CORP (JP) 2014-08-06 EP disclosed