Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286578 | 0.89 | PLAT (0.52) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1614392 | 0.89 | PLAT (0.44) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1286606 | 0.88 | PLAT (0.52) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1279373 | 0.79 | PLAT (0.59) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1278820 | 0.79 | PLAT (0.53) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1279125 | 0.78 | PLAT (0.56) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1278767 | 0.77 | PLAT (0.47) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1614469 | 0.77 | PLAT (0.47) | PLATALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL1286573 | 0.77 | PLAT (0.51) | PLATALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL1278684 | 0.76 | PLAT (0.56) | PLATALDH1A1NPSR1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796285-B2 | Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof | HEBEI MEDICAL UNIVERSITY (CN) | 2014-08-05 | — | — | US | disclosed |