SCHEMBL15927737

SCHEMBL15927737

CCCC1(C)N=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279718 0.87
SCHEMBL22076974 0.71
SCHEMBL19738685 0.70
SCHEMBL19232130 0.69
SCHEMBL22278255 0.67
SCHEMBL19738636 0.66
SCHEMBL16883905 0.65
SCHEMBL4748523 0.65
SCHEMBL22278298 0.65
SCHEMBL22861800 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 US disclosed
US-11913944-B2 Photoaffinity probes PROMEGA CORPORATION (US) 2024-02-27 US disclosed
WO-2021188978-A1 PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES ACADEMIA SINICA (TW) 2021-09-23 WO disclosed
EP-3250036-B1 SMALL MOLECULE INHIBITORS OF FIBROSIS SCRIPPS RESEARCH INST (US) 2021-05-12 EP disclosed
EP-3233041-B1 COSMETIC PROCESS FOR ATTENUATING WRINKLES OREAL (FR) 2019-01-30 EP disclosed
US-20170361131-A1 PHOTOACTIVE GRAFTED POLYSACCHARIDE AND USE THEREOF IN COSMETICS L'OREAL (FR) 2017-12-21 US disclosed
WO-2017136581-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATE MEDITOPE BIOSCIENCES, INC. (US) 2017-08-10 WO disclosed
US-20160282369-A1 LIPID PROBES AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE 2016-09-29 US disclosed
US-20160264556-A1 ITRACONAZOLE ANALOGS AND USE THEREOF UNIV JOHNS HOPKINS (US) 2016-09-15 US disclosed
WO-2016094570-A1 SMALL MOLECULE INHIBITORS OF FIBROSIS THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2016-06-16 WO disclosed
WO-2016083614-A1 PHOTOACTIVE GRAFTED POLYSACCHARIDE AND USE THEREOF IN COSMETICS L'OREAL (FR) 2016-06-02 WO disclosed
US-9346791-B2 Itraconazole analogs and use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2016-05-24 US disclosed
US-20140221393-A1 Itraconazole Analogs and Use Thereof THE JOHNS HOPKINS UNIVERSITY 2014-08-07 US disclosed