SCHEMBL15928186 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	19/20	0.67

▸	GAK	O14976	1/20	0.67

▸	ERBB2	P04626	7/20	0.61

▸	HDAC3	O15379	1/20	0.61

▸	HDAC4	P56524	1/20	0.61

▸	HDAC1	Q13547	1/20	0.61

▸	HDAC7	Q8WUI4	1/20	0.61

▸	HDAC2	Q92769	1/20	0.61

▸	HDAC10	Q969S8	1/20	0.61

▸	HDAC11	Q96DB2	1/20	0.61

▸	HDAC8	Q9BY41	1/20	0.61

▸	HDAC6	Q9UBN7	1/20	0.61

▸	HDAC9	Q9UKV0	1/20	0.61

▸	HDAC5	Q9UQL6	1/20	0.61

▸	ERBB4	Q15303	2/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15928200	0.97	EGFR (0.67)	EGFRGAKERBB2HDAC3HDAC4
SCHEMBL16212314	0.91	EGFR (0.70)	EGFRGAKERBB2ERBB4
SCHEMBL17538555	0.91	EGFR (0.66)	EGFRGAKERBB2HDAC3HDAC4
SCHEMBL2533768	0.90	EGFR (0.79)	EGFRGAKERBB2HDAC3HDAC4
SCHEMBL2533904	0.90	EGFR (0.70)	EGFRGAKERBB2ERBB4
SCHEMBL29719074	0.89	EGFR (0.69)	EGFRGAKERBB2ERBB4
SCHEMBL16212746	0.89	EGFR (0.69)	EGFRGAKERBB2ERBB4
SCHEMBL29578401	0.89	EGFR (0.80)	EGFRGAKERBB2HDAC3HDAC4
SCHEMBL31193314	0.88	EGFR (0.66)	EGFRGAKERBB2ERBB4
SCHEMBL2252507	0.88	EGFR (0.83)	EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2014117698-A1	TRICYCLIC DERIVATIVE CONTAINING QUINAZOLINE STRUCTURE, PREPARATION METHOD AND USE THEREOF	江苏奥赛康药业股份有限公司 (CN)	2014-08-07	—	—	WO	disclosed