Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15929687 | 0.89 | HTT (0.55) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL18354821 | 0.89 | HTT (0.55) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL15929688 | 0.87 | HTT (0.58) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL8736425 | 0.87 | AR (0.64) | HTTTDP1L3MBTL1POLBMAPK1 | |
| SCHEMBL15929606 | 0.85 | HTT (0.58) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL15929676 | 0.85 | HTT (0.50) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL15929689 | 0.85 | HTT (0.50) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL19318193 | 0.84 | HTT (0.57) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL19008829 | 0.84 | HTT (0.56) | HTTTDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL18969788 | 0.84 | HTT (0.56) | HTTTDP1L3MBTL1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |