Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049744 | 0.93 | ESR1 (0.58) | ESR1KLF10ALOX15ALOX12MAOB | |
| SCHEMBL18467873 | 0.88 | ESR1 (0.71) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29431900 | 0.83 | MAOB (0.57) | ESR1KLF10ALOX15ALOX12RORC | |
| SCHEMBL29445694 | 0.83 | MAOB (0.57) | ESR1KLF10ALOX15ALOX12RORC | |
| SCHEMBL125447 | 0.83 | MAOB (0.57) | ESR1KLF10ALOX15ALOX12RORC | |
| SCHEMBL29350788 | 0.83 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL35285 | 0.83 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29360146 | 0.83 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL15929636 | 0.82 | ESR1 (0.44) | ESR1ESR2ARMAOBTP53 | |
| SCHEMBL13609956 | 0.82 | ESR1 (0.55) | ESR1ESR2ARKLF10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |