SCHEMBL15930320

SCHEMBL15930320

c1ccc(-n2c(-c3ccc(-n4c5ccccc5c5ccc6oc7ccccc7c6c54)cc3)nc3ccccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
GRIA1 P42261 1/20 0.45
CACNG8 Q8WXS5 1/20 0.45
CACNG2 Q9Y698 1/20 0.45
PRKACA P17612 1/20 0.42
RPS6KB1 P23443 1/20 0.42
GSK3B P49841 1/20 0.42
ROCK1 Q13464 1/20 0.42
HTT P42858 2/20 0.42
MAPK1 P28482 1/20 0.42
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 8/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSP90AA1 P07900 1/20 0.38
MAPT P10636 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930312 0.97 ESR1 (0.52) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930442 0.92 GAA (0.45) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930450 0.91 ESR1 (0.43) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930535 0.88 ESR1 (0.47) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL17451684 0.87 ESR1 (0.46) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930316 0.87 ESR1 (0.48) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930558 0.86 ESR1 (0.48) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15073755 0.86 ESR1 (0.54) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15073676 0.86 ESR1 (0.59) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930283 0.86 ESR1 (0.59) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140217393-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. 2014-08-07 US disclosed
US-20140217393-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. 2014-08-07 US disclosed