Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930444 | 0.95 | ESR1 (0.44) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL15930310 | 0.91 | ESR1 (0.53) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL15930328 | 0.90 | ESR1 (0.49) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL20152185 | 0.90 | ESR1 (0.52) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL15930423 | 0.88 | ESR1 (0.42) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL17885306 | 0.87 | PTGER4 (0.46) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL15930450 | 0.87 | ESR1 (0.43) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL22192778 | 0.85 | KDM4E (0.38) | MEN1KMT2AMAPK1RXFP1MAPT | |
| SCHEMBL22192605 | 0.85 | KDM4E (0.38) | MEN1KMT2AMAPK1RXFP1MAPT | |
| SCHEMBL24217365 | 0.85 | KDM4E (0.36) | MAPK1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140217393-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | IDEMITSU KOSAN CO., LTD. | 2014-08-07 | — | — | US | disclosed |
| US-20140217393-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | IDEMITSU KOSAN CO., LTD. | 2014-08-07 | — | — | US | disclosed |