SCHEMBL15930491

SCHEMBL15930491

c1ccc(-c2nc3ccccc3n2-c2ccc3cc(-n4c5ccccc5c5c6oc7ccccc7c6ccc54)ccc3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
GRIA1 P42261 1/20 0.37
CACNG8 Q8WXS5 1/20 0.37
CACNG2 Q9Y698 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 2/20 0.36
HDAC1 Q13547 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
PTGS2 P35354 1/20 0.34
MAPK10 P53779 3/20 0.34
HSP90AA1 P07900 1/20 0.33
RPS6KB1 P23443 2/20 0.33
PRKACA P17612 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930390 0.94 ESR1 (0.41) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930315 0.94 ESR2 (0.51) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930503 0.93 ESR1 (0.40) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930497 0.93 ESR1 (0.44) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930459 0.93 ESR1 (0.43) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930380 0.92 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930522 0.92 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930388 0.92 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930382 0.92 ESR1 (0.44) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15930307 0.91 ESR1 (0.47) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140217393-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. 2014-08-07 US disclosed
US-20140217393-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. 2014-08-07 US disclosed