Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 9/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930690 | 0.89 | PRKCQ (0.55) | PRKCQPDE10APRKCDGSK3B | |
| SCHEMBL8966169 | 0.89 | PRKCQ (0.53) | PRKCQPDE10APRKCDGSK3BCYP2D6 | |
| SCHEMBL15930692 | 0.88 | PRKCQ (0.59) | PRKCQPDE10APRKCDGSK3B | |
| SCHEMBL8966170 | 0.88 | PRKCQ (0.52) | PRKCQPDE10APRKCDGSK3BCYP2D6 | |
| SCHEMBL15930698 | 0.88 | PRKCQ (0.53) | PRKCQPDE10APRKCDGSK3B | |
| SCHEMBL15930693 | 0.86 | PRKCQ (0.52) | PRKCQPDE10APRKCDGSK3B | |
| SCHEMBL15930701 | 0.85 | PRKCQ (0.59) | PRKCQPRKCDGSK3BCYP2D6 | |
| SCHEMBL9012518 | 0.85 | PRKCQ (0.66) | PRKCQPDE10APRKCD | |
| SCHEMBL15930694 | 0.85 | PRKCQ (0.60) | PRKCQPDE10APRKCDGSK3B | |
| SCHEMBL15930691 | 0.85 | PRKCQ (0.56) | PRKCQPDE10APRKCDGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K6 | PRKCQ 38/4885PDE10A 900/4885PRKCD 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.