Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 11/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 7/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15930683 | 0.92 | PRKCQ (0.64) | PRKCQPRKCDPRKCAALDH1A1CYP2D6 | |
| SCHEMBL15930723 | 0.91 | PRKCQ (0.57) | PRKCQPRKCDPRKCAALDH1A1GSK3B | |
| SCHEMBL15930719 | 0.90 | PRKCQ (0.56) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930684 | 0.90 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930685 | 0.90 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930675 | 0.90 | PRKCQ (0.67) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930711 | 0.89 | PRKCQ (0.55) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930718 | 0.89 | PRKCQ (0.53) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930716 | 0.87 | PRKCQ (0.55) | PRKCQPRKCDPRKCAALDH1A1PDE10A | |
| SCHEMBL15930721 | 0.87 | PRKCQ (0.53) | PRKCQPRKCDPRKCAALDH1A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K6 | PRKCQ 38/4885PRKCD 120/4885PRKCA 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.