SCHEMBL15932115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15931787	0.99	SMN1; SMN2 (0.44)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15932224	0.95	NPC1 (0.45)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15932192	0.91	SMN1; SMN2 (0.46)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15931820	0.90	SMN1; SMN2 (0.45)	TDP1NPC1RAB9ASMN1; SMN2L3MBTL1
	SCHEMBL17288601	0.86	SMN1; SMN2 (0.46)	TDP1NPC1RAB9ASMN1; SMN2L3MBTL1
	SCHEMBL20020121	0.86	TDP1 (0.47)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15931955	0.86	TDP1 (0.47)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15932085	0.85	MAPT (0.47)	TDP1NPC1RAB9ASMN1; SMN2L3MBTL1
	SCHEMBL17288673	0.85	SMN1; SMN2 (0.52)	MEN1KMT2ATDP1NPC1RAB9A
	SCHEMBL15932113	0.85	TDP1 (0.48)	MEN1KMT2ATDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.