SCHEMBL15932197

SCHEMBL15932197

CCOC(=O)c1cc(COCc2ccccc2)[nH]n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HCAR2 Q8TDS4 3/20 0.48
GABRA1 P14867 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
CSNK1D P48730 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
HPGDS O60760 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20468132 0.86 HCAR2 (0.53) POLBTP53THRBKMT2AHCAR2
SCHEMBL12703567 0.85 HCAR2 (0.67) POLBTP53THRBKMT2ASMN1; SMN2
SCHEMBL1150081 0.84 POLB (0.53) POLBTP53THRBKMT2ASMN1; SMN2
SCHEMBL15932099 0.84 HCAR2 (0.68) HCAR2
SCHEMBL1149637 0.83 POLB (0.52) POLBTP53THRBKMT2ASMN1; SMN2
SCHEMBL22435405 0.83 HCAR2 (0.56) POLBTP53THRBKMT2AHCAR2
SCHEMBL5599416 0.81 SMN1; SMN2 (0.58) POLBTP53THRBKMT2ASMN1; SMN2
SCHEMBL21607841 0.81 HCAR2 (0.66) POLBTP53THRBKMT2AHCAR2
SCHEMBL25352761 0.80 HCAR2 (0.47) POLBTP53THRBKMT2AHCAR2
SCHEMBL18695589 0.80 POLB (0.47) POLBTP53THRBKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
WO-2014119696-A1 METHOD FOR CONTROLLING ARTHROPOD PEST 住友化学株式会社 (JP) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 POLB 4377/4885TP53 4677/4885THRB 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.