Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15685092 | 0.92 | HDAC2 (0.85) | HDAC2HDAC1 | |
| SCHEMBL15653742 | 0.88 | HDAC2 (0.79) | HDAC2HDAC1 | |
| SCHEMBL1067561 | 0.88 | HDAC2 (0.77) | HDAC2HDAC1 | |
| SCHEMBL15685093 | 0.87 | HDAC2 (0.77) | HDAC2HDAC1 | |
| SCHEMBL3646210 | 0.87 | HDAC1 (1.00) | HDAC2HDAC1 | |
| SCHEMBL3645080 | 0.84 | HDAC1 (0.86) | HDAC2HDAC1 | |
| SCHEMBL3642404 | 0.83 | HDAC1 (1.00) | HDAC2HDAC1 | |
| SCHEMBL15933362 | 0.83 | HDAC2 (1.00) | HDAC2HDAC1 | |
| SCHEMBL15933369 | 0.82 | HDAC2 (1.00) | HDAC2HDAC1 | |
| SCHEMBL3640132 | 0.81 | HDAC1 (1.00) | HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040727-B2 | Histone deacetylase inhibitor of benzamides and use thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-05-26 | — | — | US | disclosed |
| US-20140221431-A1 | NOVEL HISTONE DEACETYLASE INHIBITOR OF BENZAMIDES AND USE THEREOF | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221431-A1 | NOVEL HISTONE DEACETYLASE INHIBITOR OF BENZAMIDES AND USE THEREOF | HDAC2, HDAC1, HDAC5 | HDAC2 1/4885HDAC1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.