Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933960 | 0.80 | GPBAR1 (0.48) | GPBAR1 | |
| SCHEMBL9607910 | 0.75 | NOTUM (0.58) | CNR2CYP2D6CYP2C9BRD4NOTUM | |
| SCHEMBL19949969 | 0.73 | CNR2 (0.51) | CNR2GPBAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16945783 | 0.71 | CNR2 (0.52) | CNR2GPBAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8276420 | 0.70 | CNR2 (0.46) | CNR2 | |
| SCHEMBL29941513 | 0.70 | CNR2 (0.46) | CNR2 | |
| SCHEMBL306880 | 0.69 | CNR2 (0.50) | CNR2GPBAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16750355 | 0.69 | CNR2 (0.61) | CNR2GPBAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3109454 | 0.68 | HDAC1 (0.54) | CNR2GPBAR1HSD11B1AVPR1A | |
| SCHEMBL30829767 | 0.68 | HDAC1 (0.54) | CNR2GPBAR1HSD11B1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117292-A1 | AMIDE COMPOUNDS AND PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |